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Genesis Mission Launches as US Builds Closed-Loop AI System Linking National Laboratories

 

The United States has announced a major federal scientific initiative known as the Genesis Mission, framed by the administration as a transformational leap forward in how national research will be conducted. Revealed on November 24, 2025, the mission is described by the White House as the most ambitious federal science effort since the Manhattan Project. The accompanying executive order tasks the Department of Energy with creating an interconnected “closed-loop AI experimentation platform” that will join the nation’s supercomputers, 17 national laboratories, and decades of research datasets into one integrated system. 

Federal statements position the initiative as a way to speed scientific breakthroughs in areas such as quantum engineering, fusion, advanced semiconductors, biotechnology, and critical materials. DOE has called the system “the most complex scientific instrument ever built,” describing it as a mechanism designed to double research productivity by linking experiment automation, data processing, and AI models into a single continuous pipeline. The executive order requires DOE to progress rapidly, outlining milestones across the next nine months that include cataloging datasets, mapping computing capacity, and demonstrating early functionality for at least one scientific challenge. 

The Genesis Mission will not operate solely as a federal project. DOE’s launch materials confirm that the platform is being developed alongside a broad coalition of private, academic, nonprofit, cloud, and industrial partners. The roster includes major technology companies such as Microsoft, Google, OpenAI for Government, NVIDIA, AWS, Anthropic, Dell Technologies, IBM, and HPE, alongside aerospace companies, semiconductor firms, and energy providers. Their involvement signals that Genesis is designed not only to modernize public research, but also to serve as part of a broader industrial and national capability. 

However, key details remain unclear. The administration has not provided a cost estimate, funding breakdown, or explanation of how platform access will be structured. Major news organizations have already noted that the order contains no explicit budget allocation, meaning future appropriations or resource repurposing will determine implementation. This absence has sparked debate across the AI research community, particularly among smaller labs and industry observers who worry that the platform could indirectly benefit large frontier-model developers facing high computational costs. 

The order also lays the groundwork for standardized intellectual-property agreements, data governance rules, commercialization pathways, and security requirements—signaling a tightly controlled environment rather than an open-access scientific commons. Certain community reactions highlight how the initiative could reshape debates around open-source AI, public research access, and the balance of federal and private influence in high-performance computing. While its long-term shape is not yet clear, the Genesis Mission marks a pivotal shift in how the United States intends to organize, govern, and accelerate scientific advancement using artificial intelligence and national infrastructure.

U.S DOE Announces $70 Million Funding for Improving


Funding that will support research into tech

Today, the U.S. Department of Energy (DOE) announced funding of up to $70 million to support research into technologies intended to reduce risks and increase resilience to energy delivery infrastructure from a variety of hazards, such as natural disasters, extreme weather events caused by climate change, and cyber and physical threats. 

This new competitive funding opportunity will support the advancement of next-generation innovations that fortify the resilience of America's energy systems, which include the power grid, electric utilities, pipelines, and renewable energy generation sources like wind and solar. It will be accessible to stakeholders in the public and private sectors, universities, and DOE's National Laboratories. 

President Biden's aim of net-zero emissions

Achieving President Biden's objective of a net-zero emissions economy by 2050 will require strengthening America's energy and national security, which is why the announcement made today supports the Biden-Harris Administration's efforts to construct robust and secure energy infrastructure across the nation. 

Along with making significant investments in climate resilience and adaptation, the Biden-Harris administration has also received over $50 billion from the President's Investing in America agenda

Under the direction of the DOE's Office of Cybersecurity, Electricity Security, and Emergency Response (CESER), the All-Hazards Energy Resilience initiative aims to tackle upcoming obstacles to maintain a secure and dependable supply of electricity to communities all throughout the country.  

U.S. Secretary of Energy Jennifer M. Granholm said “Making smart investments in America’s energy systems today is essential to ensuring they’re more reliable and resilient against tomorrow’s threats, while also reaching President Biden’s ambitious clean energy and climate goals.” He further added, “As we build our clean energy future, these investments will help save money in the long run by identifying and developing innovative solutions that ensure our nation’s energy infrastructure can withstand emerging threats and the challenges of a changing world.”

This grant opportunity is purposefully wide, and recipients are encouraged to develop creative and distinctive solutions that are not "one size fits all," given the rapidly changing environment and technology landscape. 

The recipients of awards will encompass all categories of energy delivery infrastructure and will tackle a wide range of possible risks related to energy generation, production, transmission, and/or distribution. 

Under this funding opportunity, CESER anticipates funding up to 25 research, development, and demonstration (RD&D) projects with budgets ranging from $500,000 to $5,000,000. Applications are encouraged from diverse teams from state and local governments, national laboratories, colleges, charity and for-profit businesses, and tribal nations.   

The projects' suggested subject topics include the following:

Cyber Research and Development: Energy systems are more vulnerable to cyberattacks as a result of the expanding digital ecosystem. These initiatives will improve cybersecurity and lower cyber threats to the infrastructure used in energy distribution. 

Development and Research on Climate Mitigation: The world's vital energy infrastructure suffers from a growing number of extreme weather events, rising sea levels, and rising temperatures. Through the development and application of creative solutions, these projects will lessen the influence of climate change on the reliability and transmission of energy.  

Development and Research on Wildfire Mitigation: Communities, ecology, and energy systems are all severely impacted by wildfires. Through these studies, possibilities to fortify infrastructure against wildfires will be identified, allowing electric companies to increase rapid recovery, operate through catastrophic occurrences, and improve resilience.

Research and Development on Physical Security: Vandalism, sabotage, and ballistic damage are some of the hazards that utility power plants must deal with when it comes to their physical security. Physical barriers, access control, and video monitoring systems are some of the modern defenses against these attacks, although they are insufficient to reduce breaches and damage. 

University-Based Research and Development: By integrating university-based research, these projects will strengthen the electric sector's cyber and cyber-physical security posture. In line with the White House Initiative on Advancing Educational Equity, Excellence, and Economic Opportunity through Historically Black Colleges and Universities, applicants must be from historically black colleges and universities. Teams must consist of academic institutions as well as owners, operators, and/or providers of solutions for the energy sector. 

Please click here for a complete list of the topic areas and more in-depth information.  

Visit their official site to learn more about DOE's initiatives to safeguard and preserve the US energy industry.